If you can have only one part 10: Vlad III Vs Nightengale

Vlad III is saddled by the trouble of being one of the worst 5* Berserkers in the game... unless you specifically have Tamamo and preferably Waver as well. Outside of Tamamo Arts teams, he's way too squishy, way too not strong, and gets far less NP than you'd expect from a Berserker with a 2-Arts deck. His NP even has worse damage than pretty much every other single-target NP. (it matches PRE-Interlude Arts NPs... AFTER its Interlude.)

Meanwhile, Nightingale's problem is exclusively that she's a Berserker - a problem that sometimes becomes immaterial and is otherwise obnoxious and painful, but not unmanageable (heck, Arts teams keep Vlad alive just fine and he's one too). Furthermore, her Noble Phantasm gets a fairly massive buff that practically turns off enemy damage for the turn it's used on - and Servants that can blank out any kind of offensive NP are extremely rare. I'd have to give this one to Nightingale, she'll simply find many more opportunities to be useful in some capacity unless you specifically have another particular 5-star.

In terms of Berserkers, any of them without the ability to monopolize on the damage potential of Madness Enhancement will fall into an odd category, as seen with these two.

Vlad III is a Berserker that can hit rather hard given he has proper support, and can stay alive relatively well with his two skills granting him a Guts and a defense buff respectively, but while his NP is capable of considerable damage, it misses out due to its somewhat unimpressive effect of gaining 15 stars and loses the damage potential of Madness Enhancement due to it being an Arts NP. Unless fielded with Tamamo or any other support that can bolster his NP gain and damage output, he pales in comparison to other contending Berserkers due to his low NP gain and his squishy Berserker classing.

Nightingale, on the other hand, is a wild card that serves as the only Berserker that specializes as a support unit. Her healing skill is rather impressive (maxing out at 4000 health), and can be upgraded to protect the target from debuffs 3 times. She also possesses the second best Buster buff in the game behind Merlin's, and with her second skill granting herself defense and additional damage to humanoids, Nightingale can provide aid as well as throw punches of her own. Her NP, while non-damaging, removes her team's debuffs, heals them, and neuters the enemy team's NP damage by half at the very least. However, she is still very vulnerable and requires support herself to keep her alive long enough to utilize her NP, given her Berserker classing. In addition, her lack of a damaging NP lowers her damage potential outside of Brave Chains.

All in all, both servants are Berserkers that are not entirely suited to their roles, but I feel Nightingale edges out due to her ability to monopolize on her Buster damage as well as fulfilling the role of a healer, buffer and protecting her team from NPs. Vlad may be more suited for DPS in Arts teams, but Nightingale has my vote for her multiple support uses and lower need for her team to babysit her.

I wonder what's the point of this comparing a Support to a DPS? 🙄

Nightingale, She just adds so much to a team, nerfing np attacks into the ground and clearing debuffs, while also healing, and providing useful buffs, and somewhat decent damage, especially against humanoid enemies like servants. Vlad, doesn't do much outside of special team comps, and even then there are better options usually. Nightingale all the way.

I've neither of them, nor have I used either from my friends list because I don't have Tamamo who is needed for Vlad, and I can't say I really could use a Berserker support. I did watch a Waver/Tamamo/Vlad team wipe the floor with the Dantes challenge, so I'm suitably impressed with that team (however, it being a whale, he had NP5 on them all, as well as 10/10/10 skills IIRC). But that isn't quite enough to earn my vote without seeing Nightingale in action.

There are no other Berserkers that are capable of spamming NP like Vlad in his preferred team. Nightingale is good and all but Merlin exists. The only thing she has over Merlin is the ability to deal more damage and remove debuffs, which is niche.
In conclusion, Vlad is stronger in a very specific team, but Nightingale is more splashable. However, a certain wizard does her role to a much greater degree. Vlad's unique role as an offensive Arts Berserker edges him over Nightingale for me.

Disclaimer: I have Vlad NP2, Waver and Tamamo

Nightingale

Who would *I* prefer to have?

I would prefer Vlad as I am trying to build an arts team around Jeanne, Tamamo, and Nero (red and bride version). Vlad fits into that perfectly.

Florence, in the other hand, fills a completely different niche that I am not working toward.

Nightingale's better although i may be a bit biased as i dont own vlad. I see plenty of Buster centric servants that nightingale would have good synergy with (due to her 3rd skill) versus the few arts supports that can cater to vlads needs.

To be honest I'm not all that impressed with Vlad...
He needs way too much babysitting to work, it also doesn't help that the support he needs are 5* as well. His NP gain from art cards is complete dog shit as well, he is totally reliable on art chains to do anything.
Since I have a (10/10/10) Tamamo and Nero Bride I decided to use him on the Dantes challenge quest. It worked out fine but the vlad support I picked was a np 3 with a lvl 100 Black Grail, so his np damage at np 1 without the CE is much less impressive.
While I don't really like the idea of a support Berseker because they die way too fast I will vote this time on Nightingale, she doesn't need so much babysitting and can be used in a vaster variety of teams. Vlad without either tamamo/bride, tamamo/waver is unusable.

I have both and I've used both extensively. With a choice of only one, I would have to go with Nightingale.

Vlad, at first glance, has quite a few good points. Battle Continuation and Morph make him hardier than many other Berserkers (Herc and Cu Alter not included of course). Vampirism helps him access his NP faster while simultaneously delaying the enemy's. His NP is a multi-hit arts type the can be used to create an Arts chain for an NP refund and his overcharge grants crit stars for the next turn.

Unfortunately, that isn't nearly enough to make up for his weaknesses, all of which can be found in those same strengths. Morph's Def buff doesn't make up for his Berserker squishiness and Battle Continuation doesn't heal for a lot, meaning a little bad luck could take him out in the same turn it revives him (which is made all the easier for the enemy by his squishiness).

Vampirism gives a hefty NP boost at 30% but his low NP gain and low hit count 1-2-2-3 (BAQE respectively) can make the remaining 70% take forever on his own. As for his NP, it is fairly strong but nothing spectacular for a Berserker, made worse by the lack of any offensive buffs of his own. And the crit stars gained, even at a high level of overcharge, is unlikely to go to him due to his low star weight, mostly going instead to his supports.

Overall, he is a poor mish-mash of survivability, offense, and a hint of support by way of his crit stars and vampirism-stall.

Nightingale, while just as squishy, has quite a bit more tankiness of her own. While only effectively half its true value due to her class (true for all Berserkers), she still has the highest HP out of all Berserkers. Her heal is massive, which can be boosted by the right CE and, after her future Rank-up, grants a 3-time 3-turn debuff resist and a 1-time 3-turn death resist. Understanding of the Human Body gives her an attack and defense buff vs humanoid enemies, and lots of bosses and challenges are Servants. Angel's Cry gives a massive Buster buff to a given Servant for 3 turns which, as others have noted, is bested only by Memelin.

Her NP is also fairly easy to access. She has a higher NP gain rate than Vlad and, despite only 2-hits on her arts cards, has 6 hits to her Quick card and 5 to her Extra. The NP itself heals by 3000 at lvl 1 and removes debuffs from the whole party while lowering the enemy's NP power by 50%. And after her interlude, she also lowers the enemy's ATK power by 50%. With that much taken off, it makes it much easier to survive an NP on the off-chance that Invincibility or Evade isn't an option for whatever reason.

In a way, Nightingale could be thought of as a squishier but more offensive-oriented Medea Lily.

Nightingale has my vote on this match-up.

I’d have to pick Nightingale. Vlad really wants Tamamo and Waver to make the most of him, where as Nightingale is more flexible with how you can use her.

I would give my vote to Vlad III.
Nightingale is a support servant that would perform really well if she wasn't a berserker. However, she is just too fraile and her berserker class won't make her any much pain compare to any 5 star DPS. Before Merlin is out, she still have somewhat of usage as a buster support, but for now, I can safely say that she would almost never be used apart from extreme rare situations such as CCC. She is simply outclassed by Merlin in almost every single aspect and Merlin can do much more and way better. Vlad however, still is the most viable and effective DPS in Art Team paired with Tamamoo and Waver and this comp can be used even in the far future and proves being one of the more effective Art team variant despite having replacements while Nightingale remains as one of the most useless servant in JP right now.
Therefore, overall, I pick Vlad III

I have Nightingale but if I could only have one, I'd choose Vlad. I will admit she's a decent support with a huge buster increase skill, on demand healing skill, and NP strength decrease. She helped me a lot in the battles against Tiamat and the last battle in Solomon with removing those annoying debuffs frequently. But she's just too fragile because of her Berserker class. I think the saddest moment in all of my battles in FGO was when she went from full health to 0 in just one turn. Plus, there's other supports out there that can do most of what she can do, minus the almost universal class disadvantage.

Vlad also is fragile, but I personally have an arts crits team and he'd be perfect in that. In fact, it's one of my favourite teams to use. He also has some decent defense measures (defense up and guts skills).