Big sister: top-class for damaging, due to her multi buffs she can deal more damage than Ozy, particularly pouring critical damage in a specific turn of brave chain NP-x-B-e.
Dio: also pretty powerful for dealing damage to enemy, but could be slight lower than Quetz due to his attacking buff is narrowed to only "attack-up" (however, this could be improved by appropriate CE and team support)
But Ozy is quite good to combine his semi-support role using his 3rd skill. For instance, in a team of Ozy-Berserker-Waver/Merlin, the Berserker can overcome his/her poor np gain via Ozy and Waver/Merlin's skills, and Waver/Merin are also beneficial to release their NP faster.
My opinion is, if you already has good Caster supports, 2030, blonde anniversary mystic code, then Quetz is answer to kill enemy. But overall Ozy is slightly better choice due to his more versatile role than Quetz.
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